Misoprostol, a synthetic analogue of prostaglandin E1, has become an integral part of obstetric practice, particularly for induction of labour. Of its many routes of administration, misoprostol buccal and oral misoprostol induction of labour are two common practices. Buccal administration includes placing the tablet against the gum on the inside of the cheek, whereas oral administration involves swallowing the tablet. Each has varying advantages and considerations upon clinical use. As induction of labor is becoming increasingly prevalent in contemporary obstetrics, knowledge of the pharmacology, effectiveness, and safety of these procedures is imperative for clinicians as well as expectant mothers.

How Misoprostol Works in Labor Induction